I've floated a few times but my first flotation tank experience was what people call a "peak experience". I got answers to big questions, overcame a lot of fear, and the experience shifted my outlook on life in a fundamental and positive way. I don't think that what is going on in the tank is just going on inside my day-to-day waking consciousness. In some ways, the experience showed me that my mind is much bigger than the physical dimensions of my skull.
Everyone should try it!